Development of a Rapid Throughput Assay for Identification of hNa(v)1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin

Voltage-gated sodium channels (VGSCs) are responsible for the generation of the action potential. Among nine classified VGSC subtypes (Na(v)1.1–Na(v)1.9), Na(v)1.7 is primarily expressed in the sensory neurons, contributing to the nociception transmission. Therefore Na(v)1.7 becomes a promising targ...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Fang, Li, Xichun, Jin, Liang, Zhang, Fan, Inoue, Masayuki, Yu, Boyang, Cao, Zhengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771989/
https://www.ncbi.nlm.nih.gov/pubmed/26891306
http://dx.doi.org/10.3390/md14020036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771989/
https://www.ncbi.nlm.nih.gov/pubmed/26891306
http://dx.doi.org/10.3390/md14020036

Ejemplares similares