The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis

The mitochondrial translocator protein (TSPO) has been implicated in CNS diseases. Here, we sought to determine the specific role of TSPO in experimental autoimmune encephalomyelitis (EAE), the most studied animal model of multiple sclerosis (MS). To fundamentally elucidate the functions of TSPO, we...

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Detalles Bibliográficos
Autores principales: Daugherty, Daniel J., Chechneva, Olga, Mayrhofer, Florian, Deng, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772008/
https://www.ncbi.nlm.nih.gov/pubmed/26925573
http://dx.doi.org/10.1038/srep22556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772008/
https://www.ncbi.nlm.nih.gov/pubmed/26925573
http://dx.doi.org/10.1038/srep22556

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