Cargando…

Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression

Eukaryotic chromosomes initiate DNA synthesis from multiple replication origins in a temporally specific manner during S phase. The replicative helicase Mcm2-7 functions in both initiation and fork progression and thus is an important target of regulation. Mcm4, a helicase subunit, possesses an unst...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheu, Yi-Jun, Kinney, Justin B., Stillman, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772014/
https://www.ncbi.nlm.nih.gov/pubmed/26733669
http://dx.doi.org/10.1101/gr.195248.115