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Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression
Eukaryotic chromosomes initiate DNA synthesis from multiple replication origins in a temporally specific manner during S phase. The replicative helicase Mcm2-7 functions in both initiation and fork progression and thus is an important target of regulation. Mcm4, a helicase subunit, possesses an unst...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772014/ https://www.ncbi.nlm.nih.gov/pubmed/26733669 http://dx.doi.org/10.1101/gr.195248.115 |