Chromosome-scale shotgun assembly using an in vitro method for long-range linkage

Long-range and highly accurate de novo assembly from short-read data is one of the most pressing challenges in genomics. Recently, it has been shown that read pairs generated by proximity ligation of DNA in chromatin of living tissue can address this problem, dramatically increasing the scaffold con...

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Detalles Bibliográficos
Autores principales: Putnam, Nicholas H., O'Connell, Brendan L., Stites, Jonathan C., Rice, Brandon J., Blanchette, Marco, Calef, Robert, Troll, Christopher J., Fields, Andrew, Hartley, Paul D., Sugnet, Charles W., Haussler, David, Rokhsar, Daniel S., Green, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772016/
https://www.ncbi.nlm.nih.gov/pubmed/26848124
http://dx.doi.org/10.1101/gr.193474.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772016/
https://www.ncbi.nlm.nih.gov/pubmed/26848124
http://dx.doi.org/10.1101/gr.193474.115

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