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Mapping nucleosome positions using DNase-seq

Although deoxyribonuclease I (DNase I) was used to probe the structure of the nucleosome in the 1960s and 1970s, in the current high-throughput sequencing era, DNase I has mainly been used to study genomic regions devoid of nucleosomes. Here, we reveal for the first time that DNase I can be used to...

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Detalles Bibliográficos
Autores principales: Zhong, Jianling, Luo, Kaixuan, Winter, Peter S., Crawford, Gregory E., Iversen, Edwin S., Hartemink, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772017/
https://www.ncbi.nlm.nih.gov/pubmed/26772197
http://dx.doi.org/10.1101/gr.195602.115