Cargando…

Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase

The Saccharomyces cerevisiae Forkhead Box (FOX) proteins, Fkh1 and Fkh2, regulate diverse cellular processes including transcription, long-range DNA interactions during homologous recombination, and replication origin timing and long-range origin clustering. We hypothesized that, as stimulators of e...

Descripción completa

Detalles Bibliográficos
Autores principales: Peace, Jared M., Villwock, Sandra K., Zeytounian, John L., Gan, Yan, Aparicio, Oscar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772018/
https://www.ncbi.nlm.nih.gov/pubmed/26728715
http://dx.doi.org/10.1101/gr.196857.115