A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening

With <2% of the human genome coding for proteins, a major challenge is to interpret the function of the noncoding DNA. Millions of regulatory sequences have been predicted in the human genome through analysis of DNA methylation, chromatin modification, hypersensitivity to nucleases, and transcrip...

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Detalles Bibliográficos
Autores principales: Diao, Yarui, Li, Bin, Meng, Zhipeng, Jung, Inkyung, Lee, Ah Young, Dixon, Jesse, Maliskova, Lenka, Guan, Kun-liang, Shen, Yin, Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772021/
https://www.ncbi.nlm.nih.gov/pubmed/26813977
http://dx.doi.org/10.1101/gr.197152.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772021/
https://www.ncbi.nlm.nih.gov/pubmed/26813977
http://dx.doi.org/10.1101/gr.197152.115

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