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A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening
With <2% of the human genome coding for proteins, a major challenge is to interpret the function of the noncoding DNA. Millions of regulatory sequences have been predicted in the human genome through analysis of DNA methylation, chromatin modification, hypersensitivity to nucleases, and transcrip...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772021/ https://www.ncbi.nlm.nih.gov/pubmed/26813977 http://dx.doi.org/10.1101/gr.197152.115 |