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Suppression of Endogenous Glucose Production by Isoleucine and Valine and Impact of Diet Composition

Leucine has been shown to acutely inhibit hepatic glucose production in rodents by a mechanism requiring its metabolism to acetyl-CoA in the mediobasal hypothalamus (MBH). In the early stages, all branched-chain amino acids (BCAA) are metabolized by a shared set of enzymes to produce a ketoacid, whi...

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Detalles Bibliográficos
Autores principales: Arrieta-Cruz, Isabel, Su, Ya, Gutiérrez-Juárez, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772043/
https://www.ncbi.nlm.nih.gov/pubmed/26891318
http://dx.doi.org/10.3390/nu8020079