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Short chain acyl-CoA dehydrogenase deficiency and short-term high-fat diet perturb mitochondrial energy metabolism and transcriptional control of lipid-handling in liver

BACKGROUND: The liver is an important site of fat oxidation, which participates in the metabolic regulation of food intake. We showed previously that mice with genetically inactivated Acads, encoding short-chain acyl-CoA dehydrogenase (SCAD), shift food consumption away from fat and toward carbohydr...

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Detalles Bibliográficos
Autores principales: Ghosh, Sujoy, Kruger, Claudia, Wicks, Shawna, Simon, Jacob, Kumar, K. Ganesh, Johnson, William D., Mynatt, Randall L., Noland, Robert C., Richards, Brenda K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772307/
https://www.ncbi.nlm.nih.gov/pubmed/26933443
http://dx.doi.org/10.1186/s12986-016-0075-0