Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans

BACKGROUND: Typhoid fever, caused by the human-restricted organism Salmonella Typhi (S. Typhi), is a major public health problem worldwide. Development of novel vaccines remains imperative, but is hampered by an incomplete understanding of the immune responses that correlate with protection. METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales: Fresnay, Stephanie, McArthur, Monica A., Magder, Laurence, Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772330/
https://www.ncbi.nlm.nih.gov/pubmed/26928826
http://dx.doi.org/10.1186/s12967-016-0819-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772330/
https://www.ncbi.nlm.nih.gov/pubmed/26928826
http://dx.doi.org/10.1186/s12967-016-0819-7

Ejemplares similares