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Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients

BACKGROUND: Neuroinflammation is increasingly recognized as contributing to the pathogenesis of depression. Key inflammatory markers as well as kynurenic acid (KYNA) and quinolinic acid (QUIN), both tryptophan metabolites, have been associated with depressive symptoms and suicidality. The aim of the...

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Detalles Bibliográficos
Autores principales: Schwieler, Lilly, Samuelsson, Martin, Frye, Mark A., Bhat, Maria, Schuppe-Koistinen, Ina, Jungholm, Oscar, Johansson, Anette G., Landén, Mikael, Sellgren, Carl M., Erhardt, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772340/
https://www.ncbi.nlm.nih.gov/pubmed/26925576
http://dx.doi.org/10.1186/s12974-016-0517-7