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Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling
Activated G(q) protein–coupled receptors (G(q)PCRs) can be desensitized by phosphorylation and β-arrestin binding. The kinetics and individual contributions of these two mechanisms to receptor desensitization have not been fully distinguished. Here, we describe the shut off of protease-activated rec...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772372/ https://www.ncbi.nlm.nih.gov/pubmed/26927499 http://dx.doi.org/10.1085/jgp.201511477 |