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Discrete distributional differential expression (D(3)E) - a tool for gene expression analysis of single-cell RNA-seq data

BACKGROUND: The advent of high throughput RNA-seq at the single-cell level has opened up new opportunities to elucidate the heterogeneity of gene expression. One of the most widespread applications of RNA-seq is to identify genes which are differentially expressed between two experimental conditions...

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Detalles Bibliográficos
Autores principales: Delmans, Mihails, Hemberg, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772470/
https://www.ncbi.nlm.nih.gov/pubmed/26927822
http://dx.doi.org/10.1186/s12859-016-0944-6