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BMS-754807 is cytotoxic to non-small cell lung cancer cells and enhances the effects of platinum chemotherapeutics in the human lung cancer cell line A549

BACKGROUND: Despite advances in targeted therapy for lung cancer, survival for patients remains poor and lung cancer remains the leading cause of cancer-related deaths worldwide. The type I insulin-like growth factor receptor (IGF-IR) has emerged as a potential target for lung cancer treatment, howe...

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Detalles Bibliográficos
Autores principales: Franks, S. Elizabeth, Jones, Robert A., Briah, Ritesh, Murray, Payton, Moorehead, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772483/
https://www.ncbi.nlm.nih.gov/pubmed/26928578
http://dx.doi.org/10.1186/s13104-016-1919-4