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Statistical optimization of tretinoin-loaded penetration-enhancer vesicles (PEV) for topical delivery
BACKGROUND: The aim of this study was to develop and optimize deformable liposome for topical delivery of tretinoin. METHODS: Liposomal formulations were designed based on the full factorial design and prepared by fusion method. The influence of different ratio of soy phosphatidylcholine and transcu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772491/ https://www.ncbi.nlm.nih.gov/pubmed/26926453 http://dx.doi.org/10.1186/s40199-016-0142-0 |