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Heme oxygenase-1 promotes neuron survival through down-regulation of neuronal NLRP1 expression after spinal cord injury

BACKGROUND: Understanding the mechanisms underlying neuronal death in spinal cord injury (SCI) and developing novel therapeutic approaches for SCI-induced damage are critical for functional recovery. Here we investigated the role of heme oxygenase-1 (HO-1) in neuroprotection after SCI. METHODS: Aden...

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Detalles Bibliográficos
Autores principales: Lin, Wen-Ping, Xiong, Gong-Peng, Lin, Qing, Chen, Xuan-Wei, Zhang, Li-Qun, Shi, Jin-Xing, Ke, Qing-Feng, Lin, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772494/
https://www.ncbi.nlm.nih.gov/pubmed/26925775
http://dx.doi.org/10.1186/s12974-016-0521-y