Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide

Autophagy plays important roles in many biological processes, but our understanding of the mechanisms regulating stem cells by autophagy is limited. Interpretations of earlier studies of autophagy using knockouts of single genes are confounded by accumulating evidence for other functions of many aut...

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Detalles Bibliográficos
Autores principales: Wang, Chenran, Chen, Song, Yeo, Syn, Karsli-Uzunbas, Gizem, White, Eileen, Mizushima, Noboru, Virgin, Herbert W., Guan, Jun-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772497/
https://www.ncbi.nlm.nih.gov/pubmed/26929451
http://dx.doi.org/10.1083/jcb.201507023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772497/
https://www.ncbi.nlm.nih.gov/pubmed/26929451
http://dx.doi.org/10.1083/jcb.201507023

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