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Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide
Autophagy plays important roles in many biological processes, but our understanding of the mechanisms regulating stem cells by autophagy is limited. Interpretations of earlier studies of autophagy using knockouts of single genes are confounded by accumulating evidence for other functions of many aut...
Autores principales: | Wang, Chenran, Chen, Song, Yeo, Syn, Karsli-Uzunbas, Gizem, White, Eileen, Mizushima, Noboru, Virgin, Herbert W., Guan, Jun-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772497/ https://www.ncbi.nlm.nih.gov/pubmed/26929451 http://dx.doi.org/10.1083/jcb.201507023 |
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