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Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation

Directional cell movements during morphogenesis require the coordinated interplay between membrane receptors and the actin cytoskeleton. The WAVE regulatory complex (WRC) is a conserved actin regulator. Here, we found that the atypical cadherin Fat2 recruits the WRC to basal membranes of tricellular...

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Detalles Bibliográficos
Autores principales: Squarr, Anna Julia, Brinkmann, Klaus, Chen, Baoyu, Steinbacher, Tim, Ebnet, Klaus, Rosen, Michael K., Bogdan, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772498/
https://www.ncbi.nlm.nih.gov/pubmed/26903538
http://dx.doi.org/10.1083/jcb.201508081