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Mathematical Modeling of Therapy-induced Cancer Drug Resistance: Connecting Cancer Mechanisms to Population Survival Rates

Drug resistance significantly limits the long-term effectiveness of targeted therapeutics for cancer patients. Recent experimental studies have demonstrated that cancer cell heterogeneity and microenvironment adaptations to targeted therapy play important roles in promoting the rapid acquisition of...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoqiang, Bao, Jiguang, Shao, Yongzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772546/
https://www.ncbi.nlm.nih.gov/pubmed/26928089
http://dx.doi.org/10.1038/srep22498