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Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis
The transcriptional state of a cell reflects a variety of biological factors, from persistent cell-type specific features to transient processes such as cell cycle. Depending on biological context, all such aspects of transcriptional heterogeneity may be of interest, but detecting them from noisy si...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772672/ https://www.ncbi.nlm.nih.gov/pubmed/26780092 http://dx.doi.org/10.1038/nmeth.3734 |