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Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis
The transcriptional state of a cell reflects a variety of biological factors, from persistent cell-type specific features to transient processes such as cell cycle. Depending on biological context, all such aspects of transcriptional heterogeneity may be of interest, but detecting them from noisy si...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772672/ https://www.ncbi.nlm.nih.gov/pubmed/26780092 http://dx.doi.org/10.1038/nmeth.3734 |