Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6

Mice carrying Collagen2a1-cre-mediated deletions of Lrp5 and/or Lrp6 were created and characterized. Mice lacking either gene alone were viable and fertile with normal knee morphology. Mice in which both Lrp5 and Lrp6 were conditionally ablated via Collagen2a1-cre-mediated deletion displayed severe...

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Detalles Bibliográficos
Autores principales: Schumacher, Cassie A, Joiner, Danese M, Less, Kennen D, Drewry, Melissa Oosterhouse, Williams, Bart O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772748/
https://www.ncbi.nlm.nih.gov/pubmed/26962465
http://dx.doi.org/10.1038/boneres.2015.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772748/
https://www.ncbi.nlm.nih.gov/pubmed/26962465
http://dx.doi.org/10.1038/boneres.2015.42

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