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Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle

Glycolytic shift is a characteristic feature of rapidly proliferating cells, such as cells during development and during immune response or cancer cells, as well as of stem cells. It results in increased glycolysis uncoupled from mitochondrial respiration, also known as the Warburg effect. Notch sig...

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Detalles Bibliográficos
Autores principales: Slaninova, Vera, Krafcikova, Michaela, Perez-Gomez, Raquel, Steffal, Pavel, Trantirek, Lukas, Bray, Sarah J., Krejci, Alena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772804/
https://www.ncbi.nlm.nih.gov/pubmed/26887408
http://dx.doi.org/10.1098/rsob.150155