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Notch stimulates growth by direct regulation of genes involved in the control of glycolysis and the tricarboxylic acid cycle
Glycolytic shift is a characteristic feature of rapidly proliferating cells, such as cells during development and during immune response or cancer cells, as well as of stem cells. It results in increased glycolysis uncoupled from mitochondrial respiration, also known as the Warburg effect. Notch sig...
Autores principales: | Slaninova, Vera, Krafcikova, Michaela, Perez-Gomez, Raquel, Steffal, Pavel, Trantirek, Lukas, Bray, Sarah J., Krejci, Alena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772804/ https://www.ncbi.nlm.nih.gov/pubmed/26887408 http://dx.doi.org/10.1098/rsob.150155 |
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