Impaired 2-AG Signaling in Hippocampal Glutamatergic Neurons: Aggravation of Anxiety-Like Behavior and Unaltered Seizure Susceptibility

BACKGROUND: Postsynaptically generated 2-arachidonoylglycerol activates the presynaptic cannabinoid type-1 receptor, which is involved in synaptic plasticity at both glutamatergic and GABAergic synapses. However, the differential function of 2-arachidonoylglycerol signaling at glutamatergic vs GABAe...

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Detalles Bibliográficos
Autores principales: Guggenhuber, Stephan, Romo-Parra, Hector, Bindila, Laura, Leschik, Julia, Lomazzo, Ermelinda, Remmers, Floortje, Zimmermann, Tina, Lerner, Raissa, Klugmann, Matthias, Pape, Hans-Christian, Lutz, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772822/
https://www.ncbi.nlm.nih.gov/pubmed/26232789
http://dx.doi.org/10.1093/ijnp/pyv091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772822/
https://www.ncbi.nlm.nih.gov/pubmed/26232789
http://dx.doi.org/10.1093/ijnp/pyv091

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