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PAQR3 controls autophagy by integrating AMPK signaling to enhance ATG14L‐associated PI3K activity

The Beclin1–VPS34 complex is recognized as a central node in regulating autophagy via interacting with diverse molecules such as ATG14L for autophagy initiation and UVRAG for autophagosome maturation. However, the underlying molecular mechanism that coordinates the timely activation of VPS34 complex...

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Detalles Bibliográficos
Autores principales: Xu, Da‐Qian, Wang, Zheng, Wang, Chen‐Yao, Zhang, De‐Yi, Wan, Hui‐Da, Zhao, Zi‐Long, Gu, Jin, Zhang, Yong‐Xian, Li, Zhi‐Gang, Man, Kai‐Yang, Pan, Yi, Wang, Zhi‐Fei, Ke, Zun‐Ji, Liu, Zhi‐Xue, Liao, Lu‐Jian, Chen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772855/
https://www.ncbi.nlm.nih.gov/pubmed/26834238
http://dx.doi.org/10.15252/embj.201592864