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Response to interferons and antibacterial innate immunity in the absence of tyrosine‐phosphorylated STAT1

Signal transducer and activator of transcription 1 (STAT1) plays a pivotal role in the innate immune system by directing the transcriptional response to interferons (IFNs). STAT1 is activated by Janus kinase (JAK)‐mediated phosphorylation of Y701. To determine whether STAT1 contributes to cellular r...

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Detalles Bibliográficos
Autores principales: Majoros, Andrea, Platanitis, Ekaterini, Szappanos, Daniel, Cheon, HyeonJoo, Vogl, Claus, Shukla, Priyank, Stark, George R, Sexl, Veronika, Schreiber, Robert, Schindler, Christian, Müller, Mathias, Decker, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772975/
https://www.ncbi.nlm.nih.gov/pubmed/26882544
http://dx.doi.org/10.15252/embr.201540726