NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2

As a genome guardian, p53 maintains genome stability by arresting cells for damage repair or inducing cell apoptosis to eliminate the damaged cells in stress response. Several nucleolar proteins stabilize p53 by interfering Mdm2–p53 interaction upon cellular stress, while other mechanisms by which n...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiaofeng, Tan, Yuqin, Zhang, Chunfeng, Zhang, Ying, Zhang, Liangliang, Ren, Pengwei, Deng, Hongkui, Luo, Jianyuan, Ke, Yang, Du, Xiaojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772976/
https://www.ncbi.nlm.nih.gov/pubmed/26882543
http://dx.doi.org/10.15252/embr.201540505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772976/
https://www.ncbi.nlm.nih.gov/pubmed/26882543
http://dx.doi.org/10.15252/embr.201540505

Ejemplares similares