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Metformin Changes the Relationship between Blood Monocyte Toll-Like Receptor 4 Levels and Nonalcoholic Fatty Liver Disease—Ex Vivo Studies

BACKGROUND: Toll-like receptor 4 (TLR4) contributes to the development of NAFLD (nonalcoholic fatty liver disease) and MetS (metabolic syndrome). It is unclear whether anti-diabetic metformin affects TLR4 expression on blood monocytes, thereby protecting or improving inflammatory parameters. Therefo...

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Detalles Bibliográficos
Autores principales: Zwolak, Agnieszka, Słabczyńska, Olga, Semeniuk, Justyna, Daniluk, Jadwiga, Szuster-Ciesielska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773077/
https://www.ncbi.nlm.nih.gov/pubmed/26930651
http://dx.doi.org/10.1371/journal.pone.0150233