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Transcriptional Regulation of CYP2B6 Expression by Hepatocyte Nuclear Factor 3β in Human Liver Cells

CYP2B6 plays an increasingly important role in xenobiotic metabolism and detoxification. The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) have been established as predominant regulators for the inductive expression of CYP2B6 gene in human liver. However, there are dramati...

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Detalles Bibliográficos
Autores principales: Li, Linhao, Li, Daochuan, Heyward, Scott, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773089/
https://www.ncbi.nlm.nih.gov/pubmed/26930610
http://dx.doi.org/10.1371/journal.pone.0150587