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Inhibition of IKKα by BAY61-3606 Reveals IKKα-Dependent Histone H3 Phosphorylation in Human Cytomegalovirus Infected Cells

Protein kinase inhibitors can be used as tools to identify proteins and pathways required for virus replication. Using virus replication assays and western blotting we found that the widely used protein kinase inhibitor BAY61-3606 inhibits replication of human cytomegalovirus (HCMV) strain AD169 and...

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Detalles Bibliográficos
Autores principales: Ho, Catherine M. K., Donovan-Banfield, I’ah Z., Tan, Li, Zhang, Tinghu, Gray, Nathanael S., Strang, Blair L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773098/
https://www.ncbi.nlm.nih.gov/pubmed/26930276
http://dx.doi.org/10.1371/journal.pone.0150339