Regional Fluctuation in the Functional Consequence of LINE-1 Insertion in the Mitf Gene: The Black Spotting Phenotype Arisen from the Mitf(mi-bw) Mouse Lacking Melanocytes

Microphthalmia-associated transcription factor (Mitf) is a key regulator for differentiation of melanoblasts, precursors to melanocytes. The mouse homozygous for the black-eyed white (Mitf(mi-bw)) allele is characterized by the white-coat color and deafness with black eyes due to the lack of melanoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Takeda, Kazuhisa, Hozumi, Hiroki, Ohba, Koji, Yamamoto, Hiroaki, Shibahara, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773177/
https://www.ncbi.nlm.nih.gov/pubmed/26930598
http://dx.doi.org/10.1371/journal.pone.0150228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773177/
https://www.ncbi.nlm.nih.gov/pubmed/26930598
http://dx.doi.org/10.1371/journal.pone.0150228

Ejemplares similares