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Regional Fluctuation in the Functional Consequence of LINE-1 Insertion in the Mitf Gene: The Black Spotting Phenotype Arisen from the Mitf(mi-bw) Mouse Lacking Melanocytes
Microphthalmia-associated transcription factor (Mitf) is a key regulator for differentiation of melanoblasts, precursors to melanocytes. The mouse homozygous for the black-eyed white (Mitf(mi-bw)) allele is characterized by the white-coat color and deafness with black eyes due to the lack of melanoc...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773177/ https://www.ncbi.nlm.nih.gov/pubmed/26930598 http://dx.doi.org/10.1371/journal.pone.0150228 |