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Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1
The cytokines IL-1α and IL-1β exert powerful pro-inflammatory actions throughout the body, mediated primarily by the intracellular signaling capacity of the interleukin-1 receptor (IL-1R1). Although Il1r1 knockout mice have been informative with respect to a requirement for IL-1R1 signaling in infla...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773179/ https://www.ncbi.nlm.nih.gov/pubmed/26930558 http://dx.doi.org/10.1371/journal.pone.0150068 |