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Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1

The cytokines IL-1α and IL-1β exert powerful pro-inflammatory actions throughout the body, mediated primarily by the intracellular signaling capacity of the interleukin-1 receptor (IL-1R1). Although Il1r1 knockout mice have been informative with respect to a requirement for IL-1R1 signaling in infla...

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Detalles Bibliográficos
Autores principales:	Robson, Matthew J., Zhu, Chong-Bin, Quinlan, Meagan A., Botschner, David A., Baganz, Nicole L., Lindler, Kathryn M., Thome, Jason G., Hewlett, William A., Blakely, Randy D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773179/ https://www.ncbi.nlm.nih.gov/pubmed/26930558 http://dx.doi.org/10.1371/journal.pone.0150068

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