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CpG Oligodeoxynucleotide Inhibits Cockroach-Induced Asthma via Induction of IFN-γ(+) Th1 Cells or Foxp3(+) Regulatory T Cells in the Lung
PURPOSE: CpG oligodeoxynucleotide (CpG-ODN), a TLR9 agonist, activates innate immunity and induces Th1 response. Although the immune modulatory effect of CpG-ODN has been extensively studied, its function in cockroach extract-induced allergic asthma has not been studied. Here, we investigated the in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773215/ https://www.ncbi.nlm.nih.gov/pubmed/26922937 http://dx.doi.org/10.4168/aair.2016.8.3.264 |