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DNA Damage and Repair Biomarkers in Cervical Cancer Patients Treated with Neoadjuvant Chemotherapy: An Exploratory Analysis

Cervical cancer cells commonly harbour a defective G(1)/S checkpoint owing to the interaction of viral oncoproteins with p53 and retinoblastoma protein. The activation of the G(2)/M checkpoint may thus become essential for protecting cancer cells from genotoxic insults, such as chemotherapy. In 52 c...

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Detalles Bibliográficos
Autores principales: Vici, Patrizia, Buglioni, Simonetta, Sergi, Domenico, Pizzuti, Laura, Di Lauro, Luigi, Antoniani, Barbara, Sperati, Francesca, Terrenato, Irene, Carosi, Mariantonia, Gamucci, Teresa, Dattilo, Rosanna, Bartucci, Monica, Vincenzoni, Cristina, Mariani, Luciano, Vizza, Enrico, Sanguineti, Giuseppe, Gadducci, Angiolo, Vitale, Ilio, Barba, Maddalena, De Maria, Ruggero, Mottolese, Marcella, Maugeri-Saccà, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773222/
https://www.ncbi.nlm.nih.gov/pubmed/26930412
http://dx.doi.org/10.1371/journal.pone.0149872