Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis

Defective primary cilia are causative to a wide spectrum of human genetic disorders, termed ciliopathies. Although the regulation of ciliogenesis is intensively studied, how it is initiated remains unclear. Here we show that type Iγ phosphatidylinositol 4-phosphate (PtdIns(4)P) 5-kinase (PIPKIγ) and...

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Detalles Bibliográficos
Autores principales: Xu, Qingwen, Zhang, Yuxia, Wei, Qing, Huang, Yan, Hu, Jinghua, Ling, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773430/
https://www.ncbi.nlm.nih.gov/pubmed/26916822
http://dx.doi.org/10.1038/ncomms10777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773430/
https://www.ncbi.nlm.nih.gov/pubmed/26916822
http://dx.doi.org/10.1038/ncomms10777

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