Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium

Bacterial pathogens produce complex carbohydrate capsules to protect against bactericidal immune molecules. Paradoxically, the pneumococcal capsule sensitizes the bacterium to antimicrobial peptides found on epithelial surfaces. Here we show that upon interaction with antimicrobial peptides, encapsu...

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Detalles Bibliográficos
Autores principales: Kietzman, Colin C., Gao, Geli, Mann, Beth, Myers, Lance, Tuomanen, Elaine I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773454/
https://www.ncbi.nlm.nih.gov/pubmed/26924467
http://dx.doi.org/10.1038/ncomms10859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773454/
https://www.ncbi.nlm.nih.gov/pubmed/26924467
http://dx.doi.org/10.1038/ncomms10859

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