Cargando…

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

Chronic stress induces signalling from the sympathetic nervous system (SNS) and drives cancer progression, although the pathways of tumour cell dissemination are unclear. Here we show that chronic stress restructures lymphatic networks within and around tumours to provide pathways for tumour cell es...

Descripción completa

Detalles Bibliográficos
Autores principales: Le, Caroline P., Nowell, Cameron J., Kim-Fuchs, Corina, Botteri, Edoardo, Hiller, Jonathan G., Ismail, Hilmy, Pimentel, Matthew A., Chai, Ming G., Karnezis, Tara, Rotmensz, Nicole, Renne, Giuseppe, Gandini, Sara, Pouton, Colin W., Ferrari, Davide, Möller, Andreas, Stacker, Steven A., Sloan, Erica K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773495/
https://www.ncbi.nlm.nih.gov/pubmed/26925549
http://dx.doi.org/10.1038/ncomms10634