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Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination
Chronic stress induces signalling from the sympathetic nervous system (SNS) and drives cancer progression, although the pathways of tumour cell dissemination are unclear. Here we show that chronic stress restructures lymphatic networks within and around tumours to provide pathways for tumour cell es...
Autores principales: | Le, Caroline P., Nowell, Cameron J., Kim-Fuchs, Corina, Botteri, Edoardo, Hiller, Jonathan G., Ismail, Hilmy, Pimentel, Matthew A., Chai, Ming G., Karnezis, Tara, Rotmensz, Nicole, Renne, Giuseppe, Gandini, Sara, Pouton, Colin W., Ferrari, Davide, Möller, Andreas, Stacker, Steven A., Sloan, Erica K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773495/ https://www.ncbi.nlm.nih.gov/pubmed/26925549 http://dx.doi.org/10.1038/ncomms10634 |
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