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Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like

Hair cells tightly control the dimensions of their stereocilia, which are actin-rich protrusions with graded heights that mediate mechanotransduction in the inner ear. Two members of the myosin-III family, MYO3A and MYO3B, are thought to regulate stereocilia length by transporting cargos that contro...

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Detalles Bibliográficos
Autores principales: Ebrahim, Seham, Avenarius, Matthew R., Grati, M’hamed, Krey, Jocelyn F., Windsor, Alanna M., Sousa, Aurea D., Ballesteros, Angela, Cui, Runjia, Millis, Bryan A., Salles, Felipe T., Baird, Michelle A., Davidson, Michael W., Jones, Sherri M., Choi, Dongseok, Dong, Lijin, Raval, Manmeet H., Yengo, Christopher M., Barr-Gillespie, Peter G., Kachar, Bechara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773517/
https://www.ncbi.nlm.nih.gov/pubmed/26926603
http://dx.doi.org/10.1038/ncomms10833