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Smac127 Has Proapoptotic and Anti-Inflammatory Effects on Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Rheumatoid arthritis (RA) is characterized by synovial inflammation and hyperplasia. Fibroblast-like synoviocytes (FLSs) are apoptosis-resistant and contribute to the pathogenesis of RA by producing cytokines and proteolytic enzymes, which degrade the extracellular matrix. We evaluated the proapopto...

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Detalles Bibliográficos
Autores principales: Lattuada, D., Gualtierotti, R., Crotta, K., Seneci, P., Ingegnoli, F., Corradini, C., Viganò, R., Marelli, O., Casnici, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773553/
https://www.ncbi.nlm.nih.gov/pubmed/26989333
http://dx.doi.org/10.1155/2016/6905678