Thioreductase-Containing Epitopes Inhibit the Development of Type 1 Diabetes in the NOD Mouse Model

Autoreactive CD4(+) T cells recognizing islet-derived antigens play a primary role in type 1 diabetes. Specific suppression of such cells therefore represents a strategic target for the cure of the disease. We have developed a methodology by which CD4(+) T cells acquire apoptosis-inducing properties...

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Detalles Bibliográficos
Autores principales: Malek Abrahimians, Elin, Vander Elst, Luc, Carlier, Vincent A., Saint-Remy, Jean-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773585/
https://www.ncbi.nlm.nih.gov/pubmed/26973647
http://dx.doi.org/10.3389/fimmu.2016.00067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773585/
https://www.ncbi.nlm.nih.gov/pubmed/26973647
http://dx.doi.org/10.3389/fimmu.2016.00067

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