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Concomitant inhibition of renin angiotensin system and Toll-like receptor 2 attenuates renal injury in unilateral ureteral obstructed mice

BACKGROUND/AIMS: There has been controversy about the role of Toll-like receptor 2 (TLR2) in renal injury following ureteric obstruction. Although inhibition of the renin angiotensin system (RAS) reduces TLR2 expression in mice, the exact relationship between TLR2 and RAS is not known. The aim of th...

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Detalles Bibliográficos
Autores principales: Chung, Sarah, Jeong, Jin Young, Chang, Yoon Kyung, Choi, Dae Eun, Na, Ki Ryang, Lim, Beom Jin, Lee, Kang Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773720/
https://www.ncbi.nlm.nih.gov/pubmed/26932402
http://dx.doi.org/10.3904/kjim.2015.004