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Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning

The calcium-sensitive type VI adenylyl cyclase (AC6) is a membrane-bound adenylyl cyclase (AC) that converts ATP to cAMP under stimulation. It is a calcium-inhibited AC and integrates negative inputs from Ca(2+) and multiple other signals to regulate the intracellular cAMP level. In the present stud...

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Detalles Bibliográficos
Autores principales: Chang, Ching-Pang, Lee, Cheng-Ta, Hou, Wen-Hsien, Lin, Meng-Syuan, Lai, Hsing-Lin, Chien, Chen-Li, Chang, Chen, Cheng, Pei-Lin, Lien, Cheng-Chang, Chern, Yijuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773765/
https://www.ncbi.nlm.nih.gov/pubmed/26932446
http://dx.doi.org/10.1038/srep22529