Mast cell degranulation is negatively regulated by the Munc13-4-binding small-guanosine triphosphatase Rab37

Mast cell degranulation is regulated by the small guanosine triphosphatases (GTPases) Rab27a and Rab27b, which have distinct and opposing roles: Rab27b acts as a positive regulator through its effector protein Munc13-4, a non-neuronal isoform of the vesicle-priming Munc13 family of proteins, whereas...

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Detalles Bibliográficos
Autores principales: Higashio, Hironori, Satoh, Yoh-ichi, Saino, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773767/
https://www.ncbi.nlm.nih.gov/pubmed/26931073
http://dx.doi.org/10.1038/srep22539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773767/
https://www.ncbi.nlm.nih.gov/pubmed/26931073
http://dx.doi.org/10.1038/srep22539

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