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Mast cell degranulation is negatively regulated by the Munc13-4-binding small-guanosine triphosphatase Rab37
Mast cell degranulation is regulated by the small guanosine triphosphatases (GTPases) Rab27a and Rab27b, which have distinct and opposing roles: Rab27b acts as a positive regulator through its effector protein Munc13-4, a non-neuronal isoform of the vesicle-priming Munc13 family of proteins, whereas...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773767/ https://www.ncbi.nlm.nih.gov/pubmed/26931073 http://dx.doi.org/10.1038/srep22539 |